Overview of .22-250 Ammo
First introduced in the 1930s as a wildcat cartridge, the .22-250 Remington began its journey as an experimental round crafted by innovative shooters and gunsmiths who wanted a high-speed, flat-shooting cartridge for varmint hunting and target shooting.
Harvey Donaldson and Grosvenor Wotkyns, two prominent figures in the early development of wildcat cartridges, played significant roles in refining the .22-250, which was originally based on the .250-3000 Savage case necked down to accept .224-caliber bullets.
Recognizing the cartridge’s tremendous potential, Remington Arms officially adopted and commercialized the .22-250 in 1965, naming it the .22-250 Remington.
This move propelled the cartridge into the mainstream and cemented its reputation as one of the fastest and flattest-shooting small-caliber centerfire rounds available. Shooters quickly embraced it for its blistering speed, exceptional accuracy, and versatility in the field.
.22-250 Remington ammo offers high muzzle velocity, often exceeding 3,800 feet per second with lighter bullet weights.
This remarkable speed enables incredibly flat trajectories, making it a favorite among varmint hunters and competitive shooters who demand precise, long-range performance.
Whether you’re targeting groundhogs, coyotes, or punching tight groups at the range, the .22-250 remains renowned for its ability to deliver consistent, pinpoint accuracy with minimal bullet drop over long distances.
The impact of the .22-250 on the shooting sports community has been profound. Hunters appreciate its ability to dispatch small to medium-sized game swiftly and humanely, while target shooters value its low recoil and superior ballistic performance.
It has earned a loyal following for offering the perfect balance between power and precision without excessive barrel wear often associated with ultra-high-velocity cartridges.
Today, the .22-250 Remington continues to thrive, supported by a wide range of factory loads and custom handloading options. Its enduring popularity underscores its status as one of the premier choices for varmint hunting, predator control, and precision shooting disciplines.
For those who demand speed, accuracy, and reliability, .22-250 ammo remains an indispensable part of any shooter’s arsenal, standing as a testament to decades of ballistic innovation and shooting excellence.
Popular 22-250 Ammunition Brands
The .22-250 Remington has earned a loyal following among hunters, varmint shooters, and target enthusiasts, thanks to its blistering speed and laser-flat trajectory. Over the years, several ammunition manufacturers have stepped up to produce top-tier .22-250 ammo, offering shooters consistent accuracy and reliable performance.
Below are some of the most trusted names that keep .22-250 Remington fans coming back for more.
Remington Ammunition
As the company that officially commercialized the .22-250 cartridge in 1965, Remington remains a cornerstone brand for this caliber. Remington’s .22-250 offerings are known for dependable brass quality, consistent powder charges, and excellent accuracy. Whether for varmints or target shooting, Remington’s loads deliver the high velocities and tight groups shooters demand.
Hornady
Hornady is synonymous with precision and innovation, and their .22-250 Remington ammo is no exception. Known for their V-MAX bullets and Superformance technology, Hornady loads provide exceptional speed, devastating terminal performance, and remarkable consistency. Varmint hunters in particular trust Hornady for long-range shots on small game.
Winchester
A household name in ammunition, Winchester produces .22-250 Remington ammo with a reputation for reliability and consistent performance. Their Varmint X line is a popular choice among predator hunters, offering polymer-tipped bullets that expand rapidly for clean, effective shots.
Federal Premium
Federal Premium brings a legacy of excellence to .22-250 Remington ammo with its American Eagle and Premium V-Shok lines. Shooters love Federal’s consistent velocities, high-quality brass, and precision-engineered bullets. The V-Shok series, featuring Nosler Ballistic Tip projectiles, is particularly favored for varmints and predators.
Nosler
Nosler is a name revered by precision shooters, and their .22-250 Remington loads reflect meticulous craftsmanship. Nosler’s Ballistic Tip and Varmageddon bullets offer rapid expansion and explosive energy transfer, making them perfect for varmints and small game. Handloaders also favor Nosler’s excellent component bullets for custom .22-250 loads.
Sellier & Bellot
For shooters seeking European quality and affordability, Sellier & Bellot offers reliable .22-250 Remington loads. Known for producing high-quality ammunition at competitive prices, S&B’s offerings perform well for both target practice and varmint hunting.
Prvi Partizan (PPU)
Prvi Partizan provides budget-friendly .22-250 ammo without sacrificing performance. Their cartridges are well-regarded for dependable brass and consistent shooting, making them an excellent choice for range sessions or high-volume varmint hunting.
Common .22-250 Ammo Types
The .22-250 Remington is a favorite among hunters, varmint shooters, and long-range enthusiasts, thanks to its blistering speed and outstanding accuracy. But choosing the right ammo type is crucial for getting the best performance from this lightning-fast cartridge.
Below is a list of the most common types of .22-250 ammunition you’ll find on the market today and how each one excels in different shooting scenarios.
Varmint and Predator Loads
By far the most popular application for .22-250 ammo is varmint and predator hunting. These loads typically feature lightweight bullets in the 40-55 grain range, often tipped with polymer points for rapid expansion.
Popular bullet types include:
- V-MAX – Hornady’s polymer-tipped design delivers explosive fragmentation, making it perfect for coyotes, prairie dogs, and other small game.
- Ballistic Tip – Nosler’s signature bullet combines a polymer tip and tapered jacket for consistent expansion and incredible accuracy.
- Soft Point (SP) – Traditional soft point bullets offer reliable expansion and moderate penetration, suitable for medium-sized predators like foxes or bobcats.
These bullets achieve extremely high muzzle velocities—sometimes exceeding 4,000 feet per second—ensuring flat trajectories and devastating terminal performance.
Match and Target Loads
For precision shooters who love punching tight groups in paper targets, match-grade .22-250 ammo is a popular choice. These loads typically use bullets between 50 and 60 grains, with a focus on uniformity and minimal ballistic deviation.
Match bullets often feature:
- Hollow Point Boat Tail (HPBT) – Designed for superior aerodynamics, these bullets reduce drag and resist wind drift for remarkable long-range accuracy.
- Open Tip Match (OTM) – Engineered for consistent bullet weight and shape, OTM designs enhance precision and group tightness.
Match ammo may have slightly lower velocities than varmint loads but offers unmatched consistency shot after shot, perfect for competitive or recreational target shooting.
Hunting Loads for Medium Game
While the .22-250 is best known for varmint control, some hunters use it for medium game like small deer under appropriate conditions. Loads intended for this purpose usually employ heavier bullets (around 55-64 grains) - with controlled expansion designs for deeper penetration.
Bullet types in this category include:
- Bonded Soft Point – Bonded bullets retain weight after impact, reducing fragmentation and improving penetration on slightly larger game.
- Partition – Nosler’s dual-core design allows for controlled expansion up front while maintaining a solid base for penetration.
Though hunters must always follow local regulations and ethical considerations, the .22-250 can be a capable choice for lighter medium game when paired with suitable ammunition.
Reloading and Custom Loads
Reloaders love the .22-250 for its versatility and performance potential. Custom handloads can be tailored for specific tasks, whether for achieving maximum velocity, tighter groups, or specialized hunting applications. Reloaders experiment with a wide range of bullet weights, powders, and seating depths to fine-tune accuracy and terminal ballistics for their rifles.
Ideal Use Cases for .22-250 Rem
Varmint Hunting
When it comes to varmint hunting, the .22-250 Remington is an undisputed champion. Its incredible muzzle velocity (often exceeding 3,800 feet per second) delivers laser-flat trajectories, allowing shooters to confidently engage small targets at long distances.
Whether you’re pursuing prairie dogs, groundhogs, or marmots, the .22-250’s explosive terminal performance ensures clean, humane kills.
- Long-range precision means fewer missed shots and less time tracking wounded game.
- High-velocity varmint bullets like polymer-tipped designs ensure rapid expansion and minimal pelt damage for those who want to preserve skins.
Predator Control
The .22-250 Remington also excels in predator hunting scenarios, offering the ideal blend of reach and stopping power for coyotes, foxes, and bobcats.
Its speed ensures minimal lead-time on fast-moving animals, while lightweight bullets create quick, devastating impact. For ranchers and farmers, it’s a trusted tool for protecting livestock and maintaining healthy wildlife populations.
- .22-250 Remington ammo offers high muzzle velocity, making it perfect for swift shots on elusive predators.
- Consistent accuracy ensures ethical, effective shots even at extended ranges.
Target Shooting and Benchrest Competition
Beyond hunting, the .22-250 has carved out a niche in the world of target shooting.
Its minimal recoil and exceptional consistency make it a favorite for benchrest shooters aiming for tight groups and bragging rights. Shooters can experiment with different bullet weights and loadings to fine-tune accuracy for their specific rifles.
- Low recoil allows shooters to spot their own shots through the scope.
- Its reputation for tiny groups makes it a favorite in competitive shooting circles.
Small Deer Hunting (Selective Use)
While primarily a varmint and predator round, some hunters use the .22-250 Rem for small deer in regions where regulations permit. With heavier bullet options (55-64 grains), this caliber can deliver sufficient energy and penetration for ethical shots on small-bodied deer.
However, careful shot placement and adherence to local hunting laws are essential.
- Suitable for lighter-bodied game under proper conditions.
- Offers less recoil than larger calibers, making it accessible for recoil-sensitive hunters.
Recreational Long-Range Shooting
For shooters who simply love stretching their shots, the .22-250 Rem is an excellent choice for recreational long-range plinking.
Its high speed and flat trajectory make hitting distant targets satisfying and fun. Plus, the thrill of watching a tiny projectile zip across a field at supersonic speeds never gets old.
- Excellent for honing long-range shooting skills.
- Affordable and widely available ammunition makes it practical for frequent practice.
Whether you’re calling in coyotes, clearing out prairie dog towns, or chasing tiny groups at the range, the .22-250 Remington is a cartridge that delivers unmatched speed, accuracy, and versatility.
Its legacy in the hunting and shooting sports communities is well-earned, proving that sometimes, smaller calibers pack an incredibly powerful punch.
22-250 Ammo FAQs
QUESTION: What is .22-250 Remington ammo best used for?
ANSWER: .22-250 Remington ammo is best known for varmint and predator hunting thanks to its extremely high muzzle velocity and flat trajectory. It’s ideal for taking small to medium-sized game like coyotes, foxes, and prairie dogs at long distances, and is also popular among target shooters for its precision and low recoil.
QUESTION: How fast does .22-250 ammo shoot?
ANSWER: One of the biggest advantages of .22-250 ammunition is speed. Factory loads often exceed 3,600 to 4,000 feet per second, depending on bullet weight. This blistering velocity is why shooters love the .22-250 Rem for long-range accuracy and minimal bullet drop.
QUESTION: Is .22-250 Remington good for deer hunting?
ANSWER: While some hunters use the .22-250 Remington for small deer where legal, it’s traditionally a varmint and predator round. Heavier bullets in the 55-64 grain range can be effective for deer, but ethical hunting requires careful shot placement and compliance with local game laws regarding minimum caliber requirements.
QUESTION: What bullet weights are available for .22-250 ammunition?
ANSWER: 22-250 ammo is available in a range of bullet weights, typically from 35 to 64 grains. Lighter bullets around 40 grains are excellent for varmints and small game, while heavier bullets offer better penetration for larger predators or small deer.
QUESTION: Is .22-250 ammo suitable for target shooting?
ANSWER: Yes! Many target and benchrest shooters love .22-250 Remington for its superb accuracy, low recoil, and flat trajectory. Its consistency makes it a top choice for those chasing tiny groups on paper at long ranges.
QUESTION: How does .22-250 compare to .223 Remington?
ANSWER: Both cartridges shoot .224-inch bullets, but the .22-250 Remington has a larger case capacity, delivering significantly higher velocity than the .223 Rem. This makes the .22-250 more suitable for longer shots and flatter trajectories, while the .223 Rem is generally more economical for higher-volume shooting.
QUESTION: Is .22-250 ammunition expensive?
ANSWER: 22-250 ammunition can be pricier than .223 Remington or .22 LR due to its high performance and larger powder charge. However, many hunters and long-range shooters consider the cost worthwhile for the cartridge’s speed, accuracy, and effectiveness in the field.
QUESTION: What types of bullets are used in .22-250 Remington ammo?
ANSWER: .22-250 Remington ammunition comes in various bullet types, including:
- Soft Point (SP): Expands on impact for hunting.
- Hollow Point (HP): Great for varmints due to rapid expansion.
- Ballistic Tip / Polymer Tip: Enhances aerodynamics for long-range shooting.
- Full Metal Jacket (FMJ): Less expansion, often used for target practice.
QUESTION: Can I reload .22-250 brass?
ANSWER: Absolutely. The .22-250 Remington is popular among reloaders because its brass is sturdy and widely available. Reloading allows shooters to fine-tune loads for specific rifles and hunting or shooting applications, though proper safety procedures and manuals should always be followed.
QUESTION: Why is .22-250 Remington so popular?
ANSWER: .22-250 Remington ammo offers high muzzle velocity, incredible accuracy, and versatile applications, from varmint hunting to target shooting. Its reputation for long-range precision and light recoil has secured its place as a favorite among hunters, competitive shooters, and firearm enthusiasts for decades.

